SKU: 2199458378

Biotin Rat Anti-Mouse CD146 Antibody (S-R606)

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Description

Biotin Rat Anti-Mouse CD146 Antibody (S-R606)Product Specification Host Rat Antigen CD146 Synonyms Cell surface glycoprotein MUC18; Gicerin; Melanoma cell adhesion molecule; Melanoma associated antigen MUC18; Muc18; Mcam Location Membrane Accession Q8R2Y2 Clone Number S R606 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 5 mg ml Conjugation Biotin Physical Appearance Liquid Storage Buffer PBS

Product Specification


Host Rat
Antigen CD146
Synonyms Cell surface glycoprotein MUC18; Gicerin; Melanoma cell adhesion molecule; Melanoma-associated antigen MUC18; Muc18; Mcam
Location Membrane
Accession Q8R2Y2
Clone Number S-R606
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.5 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1μg per million cells in 100μl volume Ms

Background

CD146, also known as melanoma cell adhesion molecule (MCAM), hemopoietic cell adhesion molecule (HEMCAM), MUC18, S-Endo1, or A32 antigen, is a highly glycosylated type I transmembrane protein and a member of the immunoglobulin superfamily. It is primarily expressed on endothelial cells and plays a crucial role in cell adhesion, migration, and proliferation. CD146 is involved in various physiological processes, such as embryonic development and tissue maintenance, and its abnormal expression is associated with diseases like cancer and inflammatory disorders. It can act as a receptor for several ligands, including laminin 421, galectin-3, and S100A8/A9, and is also a co-receptor for pro-angiogenic factor receptors like VEGFR2 and PDGFR-β.

Shipping Notes
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Exchange/Return Notes
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SKU: 2199458378

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4.8 ★★★★★
Based on 23 reviews
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Verified Purchase
Emily R
Boise, US
★★★★★ 5
Nice quality for the price
Color: Tortoise Frame/Brown Lens
Love these. Better quality than I thought they might be. Fit well, look nice.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 29, 2026
C
Verified Purchase
cmomes
Louisville, US
★★★★★ 5
Quality for lower price than brand sunnies
Color: Beige Tortoise Frame / Brown Gradient Lens
High quality for a low price. I'm someone who always loses my sunglasses so I won't allow myself to purchase any name brands. I've had my fair share of cheap sunnies for this reason. These are probably the best "off-brand" I've tried - and I've tried a lot. They are definitely polarized and are lightweight with a good fit - some of the cheaper brands are really tight on the ears and the plastic is clearly cheaply made, making them heavier. They are also a cute style with a variety of colors available. The other thing with cheaper sunglasses is they are usually not that great to peer out of. Some of them I can't wear to drive bc they are too dark, or not dark enough for glares on the road. These are great for driving - the lens coloring is just right to see well and also feel like you're not squinting. I'm buying another pair for when I inevitably lose these!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 12, 2025
P
Verified Purchase
Porkysmom
Draper, US
★★★★★ 5
Polarized sunglasses are just what I needed
Color: Tortoise Frame / Mirror Pink Lens
I really like these sunglasses. They are polarized and work great. They fit well and don't fall off when I bend over, which is important. They are light on my face and don't make marks or pressure on my nose. The color is perfect and they are really cute. They are a great value, well worth it. The cleaning cloth and bag to keep them in are a bonus. Very comfortable!
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Reviewed in the United States on April 13, 2026
M
Verified Purchase
Marzi
Omaha, US
★★★★★ 5
Great price and quality
Color: Beige Tortoise Frame / Brown Gradient Lens
Glasses are comfortable and look good. Great sun coverage
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Reviewed in the United States on June 10, 2026
A
Verified Purchase
A. Calhoun
Grantham, US
★★★★★ 5
Just buy them. There is nothing not to love!
Color: Beige Tortoise Frame / Brown Gradient Lens, Color: Beige Tortoise Frame / Brown Gradient Lens
I've had these for a year or two now and came back and ordered three more. I wear these daily because they are so comfortable and cute. A lot of sunglasses give me headaches either they are too tight or too heavy, these never do. They don't catch in your hair if you put them on your head. They don't slide down your nose when you sweat or move your head. The beige tortoiseshell is the prettiest most flattering color ever. I'm a dark winter and I struggle to find cute sunglasses other than black. So many are brown warm colors the beige violet tortoiseshell is very cool and flattering for my cool toned gals. I have a pretty normal size head and these are just a hint of oversized but in a good way. I have an oval face that leans long oval or slight heart and these are seriously flattering. I have so many photos in them they always look good. I'm going to try the all plastic version too but I honestly love the thin metal arms. Just buy these it's such a good buy and brand. I literally donated other pairs because I don't wear them anymore after discovering these. I bought obviously the beige tortoiseshell, black with gold, and the cherry. Debating on the green. My only wish is more color options. I'd love more silver arm options. Thanks WMP for these!
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Reviewed in the United States on June 9, 2026

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