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Description
CD8α Mouse mAb(SDT-126-8.3)Product Specification Host Mouse Antigen CD8a Synonyms T lymphocyte differentiation antigen T8 Leu 2, T cell surface glycoprotein CD8 alpha chain, MAL Immunogen Synthetic Peptide Location Membrane Accession P01732 Clone Number SDT 126 8. 3 Antibody Type Mouse mAb Isotype IgG1,k Application IHC P, ICC, IF Reactivity Hu Purification Protein G Concentration 1mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300
Product Specification
| Host | Mouse |
| Antigen | CD8a |
| Synonyms | T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain, MAL |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | P01732 |
| Clone Number | SDT-126-8.3 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | IHC-P, ICC, IF |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 1mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen-presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified
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