Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 26 - Aug 31
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
TBR2/Eomes Recombinant Rabbit mAb (SDT-1101-231)Product Specification Host Rabbit Antigen TBR2 Eomes Synonyms Eomesodermin homolog; T box brain protein 2 (T brain 2; TBR 2); EOMES Immunogen Synthetic Peptide Location Nucleus Accession O95936 Clone Number SDT 1101 231 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IF Reactivity Hu, Ms, Rt Positive Sample NK 92, mouse E14 embryo brain, rat E14 embryo brain Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Antigen | TBR2/Eomes |
| Synonyms | Eomesodermin homolog; T-box brain protein 2 (T-brain-2; TBR-2); EOMES |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | O95936 |
| Clone Number | SDT-1101-231 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | NK-92, mouse E14 embryo brain, rat E14 embryo brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Ms, Rt |
| IHC-P | 1:1000 | Hu, Ms, Rt |
| IF | 1:500 | Ms, Rt |
Background
TBR2/Eomes is a T-box transcription factor that plays crucial roles in various developmental processes. It is preferentially enriched in intermediate progenitors and supports cortical neurogenesis expansion. In the developing cerebral cortex, it is specifically expressed in intermediate progenitors (IPs), which are derived from radial glia progenitors and generate glutamatergic projection neurons. TBR2/Eomes is essential for the differentiation and subtype specification of these neurons, and it regulates the transcriptome by activating or repressing hundreds of direct target genes. Additionally, TBR2/Eomes is involved in the formation and maintenance of certain retinal ganglion cells. It also plays a role in the maintenance of the trophectoderm lineage by sustaining chromatin accessibility and promoting gene regulatory networks.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy