SKU: 53035550306

CCL2/MCP-1 Recombinant Rabbit mAb (SDT-1737-66)

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Description

CCL2/MCP-1 Recombinant Rabbit mAb (SDT-1737-66)Product Specification Host Rabbit Antigen CCL2 MCP 1 Synonyms C C motif chemokine 2; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor (MCAF); Monocyte chemotactic protein 1 (MCP 1); Monocyte secretory protein JE; Small inducible cytokine A2 Immunogen Recombinant Protein Accession P13500 Clone Number SDT 1737 66 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No

Product Specification


Host Rabbit
Antigen CCL2/MCP-1
Synonyms C-C motif chemokine 2; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor (MCAF); Monocyte chemotactic protein 1 (MCP-1); Monocyte secretory protein JE; Small-inducible cytokine A2
Immunogen Recombinant Protein
Accession P13500
Clone Number SDT-1737-66
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross reactivity with GRO alpha/CXCL1, GRO beta/CXCL2, IL-8
Purification Protein A
Concentration 2 mg/ml
Purity >95% by HPLC
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

CCL2, also known as monocyte chemoattractant protein-1 (MCP-1), is a small cytokine belonging to the CC chemokine family. It is primarily secreted by monocytes, macrophages, and dendritic cells, and plays a crucial role in recruiting monocytes, memory T cells, and dendritic cells to sites of inflammation or tissue injury. CCL2 exerts its effects by binding to its receptor, CCR2, and is involved in various biological processes, including leukocyte chemotaxis, regulation of apoptosis, and modulation of immune responses. This chemokine is also implicated in several diseases, such as atherosclerosis, rheumatoid arthritis, cancers and neurodegenerative disorders, due to its role in promoting inflammation and immune cell infiltration. In conclusion, CCL2 is a multifunctional chemokine with significant roles in inflammation, fibrosis, and cancer. Its expression is tightly regulated and serves as a critical mediator of immune cell recruitment and activation. The diagnostic and therapeutic potential of CCL2 makes it a promising target for addressing a wide range of diseases. Further research into the mechanisms of CCL2 regulation and its interactions with the tumor microenvironment will likely yield new insights and therapeutic strategies.

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SKU: 53035550306

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4.4 ★★★★★
Based on 26 reviews
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Riyen
Charlottesville, US
★★★★★ 5
Truly, the best we could do
Format: Kindle
An excerpt from my analysis essay I submitted for my literature course: By revisiting her family’s past from before, during, and after the Vietnam War, she gained a deeper understanding of the emotional burdens her parents carried and the sacrifices they made that defined the entirety of their lives. Bui’s illustrated graphic memoir reveals that trauma does not simply disappear over time; instead, it becomes inherited, processed, and transformed. Through this process, Thi Bui is able to move toward empathy for her parents, acceptance of who they are, and a more complete sense of self.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 21, 2026
K
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Kathy
Port Orchard, US
★★★★★ 5
Phenomenal. A must-read!
Format: Paperback
I first learned about this book only a week ago when visiting my sister for Thanksgiving in Eugene, Oregon. We went to the Jordan Schnitzer Museum of Art where I saw some work on display by the author, and there was a copy of her book available to look at, so I perused through and decided to buy it and read it. I'm so glad that I did! This is an incredible, poetic story that spans four generations, multiple wars and conflicts, and examines the fragility of the author's relationship with her parents and with her sense of place and motherhood. This book is one of the best I've read in a long time, and the art is moving and beautiful. It gave me new insight into the struggles of refugee life, and created a truly relatable narrative. I devoured this story in one Saturday. I highly recommend it.
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Reviewed in the United States on December 2, 2018
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Sav
Boise, US
★★★★★ 5
A well composed memoir
Format: Paperback
Full review on nguyentoread.com The Best We Could Do is Thi Bui's graphic memoir. Thi was born in Vietnam three months before the Vietnam War reached what we consider to be the end of the war. She came to America with her family in 1978. Bui's memoir spans multiple generations. In learning of her mother's and father's pasts, we learn the history of their parents. We see the struggles and pains of two people from very different walks of life trying to live during a time of war and chaos. We see glimpses of the agony everyone in the middle of the Vietnam War faced. Those who were not directly involved on either side but were caught in the middle of larger powers at war. This memoir more closely details the lives of her parents leading up to them arriving in America and making their life there. I was unsure if this memoir would focus largely on the experience of being a Vietnamese immigrant in America. There were parts that showed how it was for Bui's parents in a country where tensions were still high after the Vietnam War, where discrimination largely due to that was overt, and where degrees were not recognized and people who had spent their lives working and creating careers for themselves were not qualified for most work and had to hurdle multiple challenges to learn a language and complete education all over again if they wanted to provide a better life for their children. What Bui so beautifully captures in this memoir is the why behind how her parents were in raising her. Although Bui was born in Vietnam she was young when her family arrived in America. So I think her experience is one that many first generation Vietnamese-American people of my generation can understand and sympathize with. The wanting to know why their parents are the way they are but unable to ask because many have parents, like Bui's mother, who reluctantly share their stories and don't allow their children that glimpse that could help them better understand. In the panel which was most poignant to me, Bui draws her father as he looks over her work that would become The Best We Could Do. He says "You know how it was for me. And why later I wouldn't be... normal."
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Reviewed in the United States on May 20, 2019
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Noah Beitzel
West Palm Beach, US
★★★★★ 5
This book made me love my parents more
Format: Kindle
I loved the raw depictions of vietnamese history and human emotions. I recommend this book to anyone experiencing intergenerational trauma. 5 stars, this book helped me understand my father and mother just a little more, and that is priceless
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Reviewed in the United States on September 25, 2025
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Andres Hoyos
Cuba, US
★★★★★ 5
Excellent customer service
Format: Paperback
Totally recommendable.
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Reviewed in the United States on August 26, 2019

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