SKU: 71401347784

IGFBP-1 Protein, Human

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Description

IGFBP-1 Protein, HumanProduct Specification Species Human Synonyms Insulin like growth factor binding protein 1, IBP 1, IGF binding protein 1, IGFBP 1, Placental protein 12 (PP12) Accession P08833 Amino Acid Sequence Ala26Asn259, with C terminal His tag Expression System HEK293 Molecular Weight 35 38 kDa (Reducing) Purity >95% by Bis Tris PAGE and HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4

Product Specification


Species Human
Synonyms Insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1, Placental protein 12 (PP12)
Accession P08833
Amino Acid Sequence

Ala26­Asn259, with C-terminal His tag

Expression System HEK293
Molecular Weight

35-38 kDa (Reducing)

Purity >95% by Bis-Tris PAGE and HPLC
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

Reference

Trends Endocrinol Metab. 2009 May;20(4):153-62.
Cell Metab. 2015 Nov 3;22(5):811-24.

Background

IGFBP-1 is a secreted protein encoded by the IGFBP1 gene located on chromosome 7 in humans. It is a member of the insulin-like growth factor binding protein family, which consists of six high-affinity binding proteins (IGFBP-1 to -6).
Human IGFBP-1 has evolved from being viewed as a passive IGF carrier to being recognized as a dynamic, multifunctional protein with significant IGF-independent biological activities. Its primary research utility lies in its role as a sensitive biomarker for hepatic insulin sensitivity and pregnancy-related conditions. Industrially, it is harnessed for diagnostic immunoassays and explored as a novel therapeutic target. Future research is likely to further dissect its tissue-specific roles and translational potential in metabolic, bone, and neoplastic diseases.

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SKU: 71401347784

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4.7 ★★★★★
Based on 10 reviews
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Product Reviews
B
Verified Purchase
B. Stubby
New York, US
★★★★★ 3
A familiar story, just with…..less.
Format: Kindle
So, as other reviewers make clear, this is very similar to Pack Darling and The Beta. It’s much closer aligned with The Beta, in plot and maybe more like Pack Darling with characters. That being said, I don’t hate this…..but it wasn’t great either. It’s both books mentioned but just….less. Less angst, less emotion, less feeling. The plot feels very half fleshed out, and the “bad guy” feels underwhelming. I didn’t really feel any real emotions from and of the male leads, except maybe Oliver. The others fell sorta flat for me. And Mika makes herself out to be this big bad ass straight outta training and then we never see it from here again with the one fitting room incident as the exception. SPOILER: The whole, “Oh, I’m actually probably an Omega, but I don’t wanna be but I do actually wanna be but no one can ever know my secret that I do nothing to hide “ thing fell so flat. She never commutes to believing she was secretly an omega, but also mentions her “secret” a lot. It just felt so manufactured. I’m intrigued enough to read part 2 and see how the author closes everything out, but this is not one I’ll recommend or ever come back to.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 13, 2024
A
Verified Purchase
Amanda
Los Angeles, US
★★★★★ 5
A good read
Format: Kindle
A good read, just fluffy cuteness, no antagonism. I like all the characters. It could have used another round of editing however, glanfds being one error that cracked me up, and my personal pet peeve was that the author kept using the word fill instead of feel, which I promise you are not interchangeable haha, but it's definitely better than the majority of books I read on here mistake-wise.
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Reviewed in the United States on November 28, 2024
C
Verified Purchase
Cecy Melero
Boise, US
★★★★★ 4
amazing
Format: Kindle
Knot the Bride was a fantastic read! The characters were all amazing and well-developed. It was easy to like them all. Sophia, Luca, Nick, and Gavin were all perfect for each other. It was such a charming story that had me hooked the entire time. I did wish there were POVs from Luca, Nick, and Gavin but it was still an amazing book without it. I am excited to read the next book in the Willowside Omegaverse series! This is definitely a must-read for fans of omegaverse romance!. I received a free copy of this book and am voluntarily leaving a review.
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Reviewed in the United States on April 25, 2025
T
Verified Purchase
Tara
Cuba, US
★★★★★ 3
3 Star Read,
Format: Kindle
This book wasn't bad, but wasn't my cup of tea. It's highly disappointing because the storyline is so original. There is no real conflict or resolution, so the entire thing feels flat. As a lover of omegaverse books, I know there is a ton of variety out there, and ov is really up to the author. But this one is weird. Omegas have multiple scent glands all over their bodies and go into week long heats every month. Alphas have knots in the middle of their shaft instead of the base, and the knot doesn't always swell, no explanation of when or why. It doesn't engage at all when the mouth is in play. I also didn't enjoy the author's writing style. Each paragraph is only 1 or 2 sentences long, and the entire book reads very stacato. The conversations are stiff and unnatural feeling. Everything is very repetitive, both in word choice and in thought. The same thing is repeated 3 or 4 times over a single page, multiple times over. I ended up doing so much skimming. The first 50% of the book is all slow burn, and the last 50% is almost straight mediocre spice. This wouldn't have been all bad if the grammar and spelling errors didn't start at the exact same time. Tongue is repeatedly misspelled in the middle of the spice.
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Reviewed in the United States on September 14, 2024
D
Debby & Brian
New York, US
★★★★★ 5
Cozy Omegaverse
Format: Kindle
This is the true definition of Cozy Omegaverse. LA wedding coordinator meets her pack at the location for a couple’s destination wedding. Low angst because they are scent matched high heat with heats and knots. Everything you love about this genre with very little anxiety. Simply a fun experience to read and a book I will comeback to when I’m in a slump. I simply love reading this book
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 19, 2026

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