SKU: 83382905498

Biotinylated CD3E&CD3D Fc, His, Avi tag&Fc, Flag, Avi tag Heterodimer Protein, Human

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Description

Biotinylated CD3E&CD3D Fc, His, Avi tag&Fc, Flag, Avi tag Heterodimer Protein, HumanProduct Specification Species Human Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D, CD3 delta & CD3 epsilon Accession P07766 1P04234 1 Amino Acid Sequence Asp 23 Asp 126 (CD3E) with hIgG1 Fc Tag at the C Terminus, followed by polyhistidine tag and Avi tag Phe 22 Ala 105 (CD3D) with hIgG1 Fc Tag at the C Terminus, followed by Flag tag and Avi tag Expression System HEK293 Molecular Weight 43 55kDa (Reducing) Purity 95% by SDS PAGE Conjugation Unconjugated

Product Specification


Species Human
Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D, CD3 delta & CD3 epsilon
Accession P07766-1、P04234-1
Amino Acid Sequence

Asp 23 - Asp 126 (CD3E) with hIgG1 Fc Tag at the C-Terminus, followed by polyhistidine tag and Avi tag
Phe 22 - Ala 105 (CD3D) with hIgG1 Fc Tag at the C-Terminus, followed by Flag tag and Avi tag

Expression System HEK293
Molecular Weight

43-55kDa (Reducing)

Purity >95% by SDS-PAGE
Conjugation Unconjugated
Tag Avi Tag, His Tag, Flag Tag, Human IgG1 Fc
Physical Appearance Lyophilized powder
Storage Buffer

PBS, PH7.4, 5% trehalose

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Reference

1. Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function. Sci Rep. 2025 Feb 25;15(1):6769.
2. Gedeon P C , Schaller T H , Chitneni S K , et al. A rationally designed fully human EGFRvIII:CD3-targeted bispecific antibody redirects human T cells to treat patient-derived intracerebral malignant glioma.[J]. Clinical Cancer Research, 2018:clincanres.0126.2017.

Background

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 83382905498

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4.1 ★★★★★
Based on 17 reviews
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Product Reviews
C
Verified Purchase
C. J. K.
Port Orchard, US
★★★★★ 4
Good quality, not enough connections
Size: 7.1 Surround + HDMI
Good quality, I wish the sold the individual outlets because I had to buy multiple just to get 11.1 surround connections.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 13, 2025
J
Verified Purchase
Joshua Wilcox
Fort Morgan, US
★★★★★ 5
Good buy for the price.
Size: 7.2 Surround + 3 HDMI
Would have liked to use keystone inserts but this was a good alternative for the cost. Just 1 set of keystone for speakers where $10 bucks and I was able to use coax blanks and the speaker inserts from this at a 3rd of the cost.
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Reviewed in the United States on January 26, 2024
R
Verified Purchase
Razwan
Louisville, US
★★★★★ 5
Good product - quality is average.
Size: 7.2 Surround + 3 HDMI
3 hdmi outputs were a bit overkill. Ended up swapping for keystone plate with a cat6,hdmi, coax
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 3, 2017
T
Verified Purchase
Texifornia
Boise, US
★★★★★ 5
Excellent connection, and a clean look.
Size: 7.2 Surround + 3 HDMI
This worked great. I love a clean look. So I wired all the cables into the back side, in the wall. Not it looks clean and origional, like it came from the builder. I got the house and there were just a bunch of wires hanging out of the wall. This cleaned it up perfectly.
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Reviewed in the United States on October 3, 2017
D
Verified Purchase
Della
Grantham, US
★★★★★ 1
Poorly made product
Size: 7.1 Surround + HDMI
All of the tightening barrels for the bare wire install strip out when I tried to tighten down on the wire. Not just one or two but all 14 connectors failed. Very poorly made.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 11, 2024

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