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Description
MUC18/CD146 His Tag Protein, MouseProduct Specification Species Mouse Synonyms MUC18, CD146, METCAM, MCAM, Gicerin Accession Q8R2Y2 Amino Acid Sequence Val24 Val563, with C terminal 10*His
Product Specification
| Species | Mouse |
| Synonyms | MUC18, CD146, METCAM, MCAM, Gicerin |
| Accession | Q8R2Y2 |
| Amino Acid Sequence | Val24-Val563, with C-terminal 10*His VPGEEKQPVPTPDLVEAEVGSTALLKCGPSRASGNFSQVDWFLIHKERQILIFRVHQGKGQREPGEYEHRLSLQDSVATLALSHVTPHDERMFLCKSKRPRLQDHYVELQVFKAPEEPTIQANVVGIHVDRQELREVATCVGRNGYPIPQVLWYKNSLPLQEEENRVHIQSSQIVESSGLYTLKSVLSARLVKEDKDAQFYCELSYRLPSGNHMKESKEVTVPVFYPAEKVWVEVEPVGLLKEGDHVTIRCLTDGNPQPHFTINKKDPSTGEMEEESTDENGLLSLEPAEKHHSGLYQCQSLDLETTITLSSDPLELLVNYVSDVQVNPTAPEVQEGESLTLTCEAESNQDLEFEWLRDKTGQLLGKGPVLQLNNVRREAGGRYLCMASVPRVPGLNRTQLVSVGIFGSPWMALKERKVWVQENAVLNLSCEASGHPQPTISWNVNGSATEWNPDPQTVVSTLNVLVTPELLETGAECTASNSLGSNTTTIVLKLVTLTTLIPDSSQTTGLSTLTVSPHTRANSTSTEKKLPQPESKGVVGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 80-100kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Hemi X. et al. (2020) CD146/sCD146 in the Pathogenesis and Monitoring of Angiogenic and Inflammatory Diseases. Biomedicines. 8(12): 592. |
Background
CD146 is a cell adhesion molecule expressed on endothelial cells, as well as on other cells such as mesenchymal stem cells and Th17 lymphocytes. This protein also exists in a soluble form, whereby it can be detected in biological fluids, including the serum or the cerebrospinal fluid (CSF). Some studies have highlighted the significance of CD146 and its soluble form in angiogenesis and inflammation, having been shown to contribute to the pathogenesis of many inflammatory autoimmune diseases, such as systemic sclerosis, mellitus diabetes, rheumatoid arthritis, inflammatory bowel diseases, and multiple sclerosis.
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4.0 ★★★★★
Based on 30 reviews
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Product Reviews
★★★★★ 5
Puppy toy
Color: Pink "Tie Me In Knots" Shoe, Size: Small
Cute and small, perfect for a tiny puppy.
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Reviewed in the United States on April 18, 2026
★★★★★ 5
Cute gift for a dog!
Stylish!
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Reviewed in the United States on May 19, 2026
★★★★★ 5
Cute
Cute bag for my dog
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Reviewed in the United States on May 8, 2026
★★★★★ 5
Every Glamorous Pup Needs Pawfum
Color: Black Noir Pawfum, Size: One Size, Color: Black Noir Pawfum, Size: One Size
As a sophisticated young lady with impeccable taste, I can confidently say that the Chewnel Noir Pawfum is a must-have for every fashionable pup.
The moment I got my paws on it, I knew it was special. It’s soft, adorable, and the perfect size for carrying around the house, chewing, cuddling, and showing off during my puppy playdates. It adds just the right amount of luxury to my toy collection.
Not only does it look fabulous in photos, but it also keeps me entertained for hours. My humans can’t stop laughing every time they see me strutting around with my designer “pawfum.”
If you’re a puppy who loves the finer things in life, this toy deserves a spot in your collection.
Five paws from Pennie Lou! Because every glamorous girl needs her signature scent.
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Reviewed in the United States on June 7, 2026
★★★★★ 5
Nice dig you
Color: Black Noir Pawfum, Size: One Size
So cute and my yorkies love it
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Reviewed in the United States on April 25, 2026
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