SKU: 44239136543

CD38 Fc Chimera Protein, Human

Sale price$270.00 Regular price$300.00
Save 10%

Pay in installments of $75.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 20 - Aug 25

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

CD38 Fc Chimera Protein, HumanProduct Specification Species Human Synonyms ADPRC1; cADPR1; ADPRC 1 Accession P28907 1 Amino Acid Sequence Val43 Ile300, with C terminal Human IgG Fc

Product Specification


Species Human
Synonyms ADPRC1; cADPR1; ADPRC 1
Accession P28907-1
Amino Acid Sequence

Val43-Ile300, with C-terminal Human IgG Fc

VPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEIIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Expression System HEK293
Molecular Weight

68-72kDa (Reducing)

Purity

>90% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag Human Fc Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Background

Cluster of differentiation 38 (CD38) is a multifunctional extracellular enzyme on the cell surface with NADase and cyclase activities. As a NADase, CD38 produces adenosine through the adenosine energy pathway to cause immunosuppression. As a cell surface receptor, CD38 is necessary for immune cell activation and proliferation. Previous studies suggested that CD38 plays an important role in the regulation of macrophage function.  Therefore, as a new marker of macrophages, the effect of CD38 on macrophage proliferation, polarization and function, its possible mechanism; CD38 is not only expressed in human immune cells, such as lymphocytes and plasma cells, but also is abnormally expressed in a variety of tumor cells, which is closely related to the occurrence and development of tumors.  The role of CD38 in immune cells ranges from modulating cell differentiation to effector functions during inflammation, where CD38 may regulate cell recruitment, cytokine release, and NAD availability. In line with a role in inflammation, CD38 appears to also play a critical role in inflammatory processes during autoimmunity, although whether CD38 has pathogenic or regulatory effects varies depending on the disease, immune cell, or animal model analyzed.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 44239136543

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.9 ★★★★★
Based on 28 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
T
Verified Purchase
Tida Coffman
Lake Worth, US
★★★★★ 5
Great hit!
Format: Paperback
Our grandson loved the story and appreciated the humor. He asked for the other editions! Wants to know more about the dragon.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 20, 2026
A
Verified Purchase
Amazon Customer
Carnegie, US
★★★★★ 5
Seven Year Old Son Loves it!
Format: Kindle
I read this with my seven year old son and he really loved it. It kept him interested and engaged the whole time. I hope there is more to come in this series from his perspective!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 12, 2025
C
Verified Purchase
catlover
Belleville, US
★★★★★ 5
Dragon Diaries 🐲
Format: Paperback
A fun addition to her chapter book series! My daughter and I loved this book. Perfectly goes with the Sprinkles and Unicorn books and we can't wait for more!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 8, 2025
K
Verified Purchase
Kelsey F.
Omaha, US
★★★★★ 5
Great book!!
Format: Paperback
The boys and girls in my class are both excited for this title! I am excited to read it aloud to them!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 7, 2025
V
Verified Purchase
VALENCA NOVOA
Boise, US
★★★★★ 5
I Loved It
Format: Kindle
This was my first time reading a book by Elle Alexanda, and it definitely won’t be my last! I was absolutely captivated by the Lou/Ava love story. I found Lou’s vulnerability so endearing. It was an excellent read, and I wish it were available as an audiobook. The story was a slow burn, but it kept me hooked. The flirting and banter between Lou and Ava were so entertaining. I didn’t want the story to end! Well done, Elle!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 21, 2025

recommand products