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Description
S-RMab®CD8α Recombinant Rabbit mAb (SDT-142-52)Product Specification Host Rabbit Antigen CD8 Synonyms Lyt 2 Immunogen Synthetic Peptide Location Cell membrane Accession P01731 Clone Number SDT 142 52 Antibody Type Rabbit mAb Application WB, IHC P, FCM, IF Reactivity Ms Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 20 C as supplied Dilution
Product Specification
| Host | Rabbit |
| Antigen | CD8α |
| Synonyms | Lyt-2 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P01731 |
| Clone Number | SDT-142-52 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, FCM, IF |
| Reactivity | Ms |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1:50 | |
| WB | 1:1000 | |
| IF | 1:1000 | |
| IHC-P | 1:500 |
Background
CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy.In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
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Exchange/Return Notes
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