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Description
Human CD14, His tagProduct Specification Species Human Synonyms Myeloid cell specific leucine rich glycoprotein Accession P08571 Amino Acid Sequence Protein sequence(P08571, Thr20 Met344, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | Myeloid cell-specific leucine-rich glycoprotein |
| Accession | P08571 |
| Amino Acid Sequence | Protein sequence(P08571, Thr20-Met344, with C-10*His) TTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:36.7kDa Actual:50-55kDa |
| Purity | ＞90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns such as lipoteichoic acid.
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4.4 ★★★★★
Based on 8 reviews
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Product Reviews
★★★★★ 1
Worthless. Tore on first use.
Flavor Name: XL silicone socks 2 pairs
The first time I put these on my feet, the whole toe broke right through. They were a proper fit and my feet are well pedicured. Just very poor quality. I don’t recommend.
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Reviewed in the United States on August 2, 2024
★★★★★ 5
Best fit!
Flavor Name: XL silicone socks 2 pairs
Search no further, these are the BEST! They are smazing at conforming to the shape of your feet. They fit snuggly with no sags/bags or uncomfortable pressure or squeezing of your toes.
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Reviewed in the United States on March 8, 2025
★★★★★ 4
Helps dry, cracked feet
Flavor Name: XL silicone socks 2 pairs
We use these on my husband’s cracked feet in the winter and put on a thick cream under these socks. They are nice because hair, dirt and that kind of stuff doesn’t stick to the outside. I do wish them came in more sizes and colors. They were a little small for my husband, but still worked good enough. My husband isn’t thrilled about wearing pink socks around the house. At least it’s just around the house and not out in public though.
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Reviewed in the United States on March 6, 2025
★★★★★ 5
Be aware! Once they are on, do not walk! 😂
Flavor Name: XL silicone socks 2 pairs
I absolutely love these things. But the first time I put them on in the living room. The walk to my bedroom was VERY interesting 😂😂😂 I now know I need to put them on and hang out for a bit, or simply go to bed. They do exactly what I need them to do. Feet feel great afterwards! With the right lotion, only need to use one every couple of weeks.
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Reviewed in the United States on January 10, 2025
★★★★★ 5
Transformed my feet
Flavor Name: XL silicone socks 2 pairs
After trying several other brands that actually my size did not have the luxury feeling of these. T although x large they have the BEST feel and function. I put lotion on then slip them on and within a few minutes my dry cracked heals are soft. Really a nice product.
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Reviewed in the United States on July 24, 2024