SKU: 75851117945

Human Immunoglobulin kappa constant, His tag

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Description

Human Immunoglobulin kappa constant, His tagProduct Specification Species Human Synonyms Ig kappa chain C region, Ig kappa chain C region AG, Ig kappa chain C region CUM, Ig kappa chain C region EU, Ig kappa chain C region OU, IGKC Accession P01834 Amino Acid Sequence Protein sequence(P01834, Arg1 Cys107, with C 10*His) RTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECGGGGSHHHHHHHHHH Expression System CHO Molecular Weight Theoretical:

Product Specification


Species Human
Synonyms Ig kappa chain C region, Ig kappa chain C region AG, Ig kappa chain C region CUM, Ig kappa chain C region EU, Ig kappa chain C region OU, IGKC
Accession P01834
Amino Acid Sequence

Protein sequence(P01834, Arg1-Cys107, with C-10*His) RTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECGGGGSHHHHHHHHHH

Expression System CHO
Molecular Weight Theoretical:13.4kDa Actual:14kDa
Purity

>95% by SDS-PAGE

Endotoxin <1EU/μg
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin). There are two types of light chain in humans: kappa (κ) chain and lambda (λ) chain. Individual B-cells in lymphoid tissue possess either kappa or lambda light chains, but never both together. Specific rearrangement of lambda light chain of immunoglobulins can lead to loss of some protein coding genes. Using immunohistochemistry, it is possible to determine the relative abundance of B-cells expressing kappa and lambda light chains. If the lymph node or similar tissue is reactive, or otherwise benign, it should possess a mixture of kappa positive and lambda positive cells. If, however, one type of light chain is significantly more common than the other, the cells are likely all derived from a small clonal population, which may indicate a malignant condition, such as B-cell lymphoma.

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SKU: 75851117945

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4.8 ★★★★★
Based on 26 reviews
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Raquel
Houston, US
★★★★★ 5
Won’t go a day without it
Size: 2.32 Pound (Pack of 1), Style: New, Size: 2.32 Pound (Pack of 1), Style: New
So much better than the sugar version which has SOOOO much sugar it gave me heartburn. Yes, the sugar version is tasty like Tang, but that sugar gave me indigestion. The aspartame version was disgusting. This Stevia is awesome. Because it doesn’t have tons of sugar, you only need 2 heaping teaspoons instead of 2 tablespoons of the regular. I think it’s delicious and also has natural coloring, the sugar version has artificial dyes. I drink it everyday and my GI tract has never been happier. Only one small issue, this size container (~14 oz) is narrow, so buy the bigger bottle (23 or 34?) so you can reach in to scoop it easily. I have zero bloating or gas and sometimes take it more than once per day. It supposedly decreases appetite if taken before meals. It expands in your gut! Perfect. Just don’t take it within 2 hours of oral meds/vitamins as it can supposedly decrease gut absorption. Enjoy the results!!
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Reviewed in the United States on July 3, 2025
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Anna Z
Natrona Heights, US
★★★★★ 4
Lower Cholesterol and Better Digestion, Even if the Taste Takes Getting Used To
Size: 2.32 Pound (Pack of 1), Style: New
I started using this fiber supplement after my doctor recommended it to help manage my cholesterol. I like that it’s plant-based and sugar-free, and it’s easy to mix into water. After taking it regularly, I’ve noticed a positive impact on my digestion, and I’m hopeful it will help with my cholesterol in the long run. The only thing is that the taste and texture aren’t quite what I expected — it’s a bit like protein powder. Still, the health benefits make it worth continuing
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Reviewed in the United States on August 8, 2025
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Verified Purchase
K. Hansen
Birmingham, US
★★★★★ 5
Good taste
Size: 2.32 Pound (Pack of 1), Style: New
Tastes like tang. Take daily to reduce cholesterol.
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Reviewed in the United States on February 25, 2026
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Alison Lindley
Chelsea, US
★★★★★ 5
Great Seller and Product
Size: 2.32 Pound (Pack of 1), Style: New
Wonderful customer service!! I needed to refund as I ordered by mistake, and they refunded right away!! Will order again from this seller.
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Reviewed in the United States on March 26, 2026
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Robert Kern
Whiting, US
★★★★★ 5
Great Product, Works as Advertised
Flavor Name: Unflavored, Size: 1.46 Pound (Pack of 1)
This product works exactly as described. It makes BM's smoother and gentler. I personally use the unflavored, no sweeteners added version, and honestly, it does not taste very good, but I feel that the results are worth it, and I do not like adding extra sweeteners or flavorings to my diet. I have used this product for many years and have found that about 1 1/2 to 2 tbsps in 12 ounces of water works the best for me. You will need to experiment a bit to find the ratio that works best for you. I recommend that you start on the low side and gradually increase the amount of Metamucil as needed.
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Reviewed in the United States on March 26, 2026

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