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Description
Human CSF1R, His tagProduct Specification Species Human Synonyms CSF 1 receptor (CSF 1 R; CSF 1R; M CSF R), Proto oncogene c Fms, CD115, FMS Accession P07333 Amino Acid Sequence Protein sequence(P07333, Ile20 Asn320, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | CSF-1 receptor (CSF-1-R; CSF-1R; M-CSF-R), Proto-oncogene c-Fms, CD115, FMS |
| Accession | P07333 |
| Amino Acid Sequence | Protein sequence(P07333, Ile20-Asn320, with C-10*His) IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:34.6kDa Actual:50kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.
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4.5 ★★★★★
Based on 15 reviews
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Product Reviews
★★★★★ 1
Sizing is not accurate!
Size: 9 Years, Color: Light Blue
I bought this for my granddaughter, who is 8 years old, and typically wears a size 8. I purchased the size 9, she likes oversized hoodies, even though the add already says it’s oversized. It was MAYyBE a size 6, it was tight on my six year old granddaughter. I sent it back, and am not reordering. I’m not going to keep guessing on sizing. I want to know that when I order the size she wears in Nike, Adidas, Target,etc. , that it’s going to be the same, and not have to keep returning items…
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Reviewed in the United States on July 26, 2025
★★★★★ 5
Take the chill off
Size: 3T, Color: Black
Loved these and they fit. Nice and warm for a chilly summer evening at the beach, and looked great with summer pastels.
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Reviewed in the United States on January 27, 2026
★★★★★ 5
Perfect for DIY 🖤
Size: 2T, Color: Black, Size: 2T, Color: Black
I make hoodies for my toddler with them. They’re soooo cute!!! Kept him pretty warm too. 🖤
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Reviewed in the United States on December 27, 2025
★★★★★ 5
True to size, good quality
Size: 3T, Color: White, Size: 3T, Color: White
Great quality sweatshirts. I bought white to tie dye. They held the dye really well! They are true to size, but a little bit longer than most shirts. They fit my kids really well. They have also held up well in the wash, no shrinking at all!
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Reviewed in the United States on April 7, 2025
★★★★★ 5
Durable and Warm
Size: 4T, Color: Orange
This is a great quality and my son says its really warm. Some hoodies can be a bit to thin, but this one was a little thicker and a great weight for those chilly days. I even applied some Cricut-cut HTV designs to the front and they worked really well on this fabric. It washes up great and has held up really well to my toddler's abuse!
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Reviewed in the United States on April 29, 2025