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Description
IL-4R alpha/CD124 His Tag Protein, MouseProduct Specification Species Mouse Synonyms IL 4R alpha, CD124, IL4R, IL4RA Accession P16382 Amino Acid Sequence Ile26 Arg233, with C terminal 8*His IKVLGEPTCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFSENLTCIPRNSASTVCVCHMEMNRPVQSDRYQMELWAEHRQLWQGSFSPSGNVKPLAPDNLTLHTNVSDEWLLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRSQILTGTWSEWSPSITWYNHFQLPLIQRGGGSHHHHHHHH Expression System HEK293 Molecular Weight 35 45kDa Purity >95% by SDS PAGE Endotoxin
Product Specification
| Species | Mouse |
| Synonyms | IL-4R alpha, CD124, IL4R, IL4RA |
| Accession | P16382 |
| Amino Acid Sequence | Ile26-Arg233, with C-terminal 8*His IKVLGEPTCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFSENLTCIPRNSASTVCVCHMEMNRPVQSDRYQMELWAEHRQLWQGSFSPSGNVKPLAPDNLTLHTNVSDEWLLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRSQILTGTWSEWSPSITWYNHFQLPLIQRGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 35-45kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Nelms K. et al. (2003) The IL-4 receptor: signaling mechanisms and biologic functions. Annual Review of Immunology. 17: 701-738. |
Background
IL-4Rα is a member of the hematopoietin receptor superfamily. Among the defining features of the members of this superfamily of receptors are shared structural motifs in the extracellular region, which consists of type III fibronectin domains. These motifs include conserved paired Cys residues and, in the membrane proximal region, a WSXWS motif. The latter has been proposed to be required for maintaining the receptor in a conformation favorable to cytokine binding. Structural alterations in the IL-4Rα extracellular region may result in altered receptor signaling capabilities. Indeed, a variant of the human IL-4Rα chain containing a Ile50Val substitution was isolated from atopic individuals and has been shown to enhance signal transduction resulting in the increased production of IgE.
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4.8 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
I like this brand of clothing, let’s keep them around.
Size: X-Large, Color: Brown
Great quality great fit.
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Reviewed in the United States on May 5, 2026
★★★★★ 5
Well made but on the small side. I recommend ordering one size bigger than your usual size
Size: Large, Color: Pure Black (Retro Rose)
The fit on this shirt ran slightly smaller for me being a slim fit, so I order the next size up. Getting the next size up gave me a perfect fit. The material is soft and comfortable. I will likely consider similar shirts in the future. I recommend the product.
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Reviewed in the United States on April 30, 2026
★★★★★ 5
Cowboy shirt
Size: Large, Color: White
Good quality. Fit and finish seem nice for the price. Look like a cowboy! Yeee haaaaaw. Wrinkles easy in dryer, don’t let it sit for long.
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Reviewed in the United States on March 4, 2026
★★★★★ 4
Very nice shirt -Good Quality
Size: XX-Large, Color: Red (Retro Rose)
My husband is 6'1, weighs 178 pounds and normally wears a medium or large. Just for reference his pant size is a 32-34 depending on the brand. We ordered a large due to the fact the shirt appeared to be fitted more at the waist and from looking at the description I knew it would not have much stretch due to the satin type material. I was right. The large fit perfect and hung well. My husband use to be very large in shoulders and arms, but with age he has lost muscle mass, and recently lost a lot in his belly, so usually mediums fit perfect now. But when he put his large on, a medium would not have fit good to be comfortable & give proper fit in stomach area, so glad we went with the large.
The shirt was purchased to go on a Virgin Cruise for Scarlett night, and he plans to wear black pants with it as in the picture the company posted, and this shirt will be perfect for that. It is a nice shirt, good quality, and if someone wanted it for an event/cruise or just for a night to dress up, especially for a Caribbean/Spanish or Latin dance theme, this shirt is a perfect look to me. Buy it, you will not be disappointed. He has not worn it yet, not washed it, but I would not put in it with other colors, may fade a little like reds do, and definitely, only dry on low/delicate. May need a pressing/steaming, but overall, it was not horribly wrinkled when we received it. A toss in the dryer may just do the trick. Was delivered on time as it said it would. Hope this info helps you.
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Reviewed in the United States on January 14, 2024
★★★★★ 5
Yeehaw!
I like this shirt. Very fancy yet western.
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Reviewed in the United States on January 20, 2026